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Molecular Dynamics and Physical Stability of Ibuprofen in Binary Mixtures with an Acetylated Derivative of Maltose

[Image: see text] In this paper, we explore the strategy increasingly used to improve the bioavailability of poorly water-soluble crystalline drugs by formulating their amorphous solid dispersions. We focus on the potential application of a low molecular weight excipient octaacetyl-maltose (acMAL) t...

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Detalles Bibliográficos
Autores principales:	Grzybowska, Katarzyna, Grzybowski, Andrzej, Knapik-Kowalczuk, Justyna, Chmiel, Krzysztof, Woyna-Orlewicz, Krzysztof, Szafraniec-Szczęsny, Joanna, Antosik-Rogóż, Agata, Jachowicz, Renata, Kowalska-Szojda, Katarzyna, Lodowski, Piotr, Paluch, Marian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2020
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7467776/ https://www.ncbi.nlm.nih.gov/pubmed/32584584 http://dx.doi.org/10.1021/acs.molpharmaceut.0c00517

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