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Aspects cliniques thérapeutiques et pronostiques des tumeurs germinales malignes de l’ovaire: expérience tunisienne de 21 ans

INTRODUCTION: malignant germ cell tumors of the ovary (TGMO) are rare ovarian tumors. Each histological type can have clinical and therapeutic particularities which it is important to know. The objective was to report and analyze the particularities of the epidemiological, diagnostic, anatomopatholo...

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Autores principales: Ghaddab, Imen, Briki, Raja, Bouguizene, Sassi, Khairi, Hedi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7467897/
https://www.ncbi.nlm.nih.gov/pubmed/32952822
http://dx.doi.org/10.11604/pamj.2020.36.178.23916
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author Ghaddab, Imen
Briki, Raja
Bouguizene, Sassi
Khairi, Hedi
author_facet Ghaddab, Imen
Briki, Raja
Bouguizene, Sassi
Khairi, Hedi
author_sort Ghaddab, Imen
collection PubMed
description INTRODUCTION: malignant germ cell tumors of the ovary (TGMO) are rare ovarian tumors. Each histological type can have clinical and therapeutic particularities which it is important to know. The objective was to report and analyze the particularities of the epidemiological, diagnostic, anatomopathological, therapeutic and prognostic data of TGMO in Tunisian context. METHODS: this study is a retrospective descriptive and analytical survey carried out at the Gynecology-Obstetrics departments of the CHU FARHAT HACHED in Sousse over a period of 21years collecting all the cases of patients having been treated for TGMO. RESULTS: a total number of 30 files was eligible for our study. The average age of our patients was 22years. The majority of patients were in a period of genital activity. The reason for the consultation was mainly represented by abdomino-pelvic pain followed by an increase in abdominal volume. Abdominopelvic ultrasound was performed in 80% of our patients showing a suspicious appearance of malignancy in 100% of them. For our patients, 70% were approached by median laparotomy given the tumor volume and only 30% by laparoscopy. 76.7% had conservative treatment. The predominance of stage I was noted while there was no case in stage IV. The overall survival for all stages was 96.7% at 2years and 85.7% at 5years and 75.8% at 10years. The prognostic factors of the TGMOs isolated from our series were the consultation time greater than 6 months, the age greater than 30years, the tumor size greater than 20cm and the tumor stage. CONCLUSION: it would be more interesting to bring together the other cases of TGMO diagnosed in other cancer registries in the country in order to establish a national register of rare ovarian tumors.
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spelling pubmed-74678972020-09-17 Aspects cliniques thérapeutiques et pronostiques des tumeurs germinales malignes de l’ovaire: expérience tunisienne de 21 ans Ghaddab, Imen Briki, Raja Bouguizene, Sassi Khairi, Hedi Pan Afr Med J Research INTRODUCTION: malignant germ cell tumors of the ovary (TGMO) are rare ovarian tumors. Each histological type can have clinical and therapeutic particularities which it is important to know. The objective was to report and analyze the particularities of the epidemiological, diagnostic, anatomopathological, therapeutic and prognostic data of TGMO in Tunisian context. METHODS: this study is a retrospective descriptive and analytical survey carried out at the Gynecology-Obstetrics departments of the CHU FARHAT HACHED in Sousse over a period of 21years collecting all the cases of patients having been treated for TGMO. RESULTS: a total number of 30 files was eligible for our study. The average age of our patients was 22years. The majority of patients were in a period of genital activity. The reason for the consultation was mainly represented by abdomino-pelvic pain followed by an increase in abdominal volume. Abdominopelvic ultrasound was performed in 80% of our patients showing a suspicious appearance of malignancy in 100% of them. For our patients, 70% were approached by median laparotomy given the tumor volume and only 30% by laparoscopy. 76.7% had conservative treatment. The predominance of stage I was noted while there was no case in stage IV. The overall survival for all stages was 96.7% at 2years and 85.7% at 5years and 75.8% at 10years. The prognostic factors of the TGMOs isolated from our series were the consultation time greater than 6 months, the age greater than 30years, the tumor size greater than 20cm and the tumor stage. CONCLUSION: it would be more interesting to bring together the other cases of TGMO diagnosed in other cancer registries in the country in order to establish a national register of rare ovarian tumors. The African Field Epidemiology Network 2020-07-13 /pmc/articles/PMC7467897/ /pubmed/32952822 http://dx.doi.org/10.11604/pamj.2020.36.178.23916 Text en Copyright: Imen Ghaddab et al. https://creativecommons.org/licenses/by/4.0 The Pan African Medical Journal (ISSN: 1937-8688). This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Ghaddab, Imen
Briki, Raja
Bouguizene, Sassi
Khairi, Hedi
Aspects cliniques thérapeutiques et pronostiques des tumeurs germinales malignes de l’ovaire: expérience tunisienne de 21 ans
title Aspects cliniques thérapeutiques et pronostiques des tumeurs germinales malignes de l’ovaire: expérience tunisienne de 21 ans
title_full Aspects cliniques thérapeutiques et pronostiques des tumeurs germinales malignes de l’ovaire: expérience tunisienne de 21 ans
title_fullStr Aspects cliniques thérapeutiques et pronostiques des tumeurs germinales malignes de l’ovaire: expérience tunisienne de 21 ans
title_full_unstemmed Aspects cliniques thérapeutiques et pronostiques des tumeurs germinales malignes de l’ovaire: expérience tunisienne de 21 ans
title_short Aspects cliniques thérapeutiques et pronostiques des tumeurs germinales malignes de l’ovaire: expérience tunisienne de 21 ans
title_sort aspects cliniques thérapeutiques et pronostiques des tumeurs germinales malignes de l’ovaire: expérience tunisienne de 21 ans
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7467897/
https://www.ncbi.nlm.nih.gov/pubmed/32952822
http://dx.doi.org/10.11604/pamj.2020.36.178.23916
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