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Hippocampal alterations in glutamatergic signaling during amyloid progression in AβPP/PS1 mice
Our previous research demonstrated that soluble amyloid-β (Aβ)(42), elicits presynaptic glutamate release. We hypothesized that accumulation and deposition of Aβ altered glutamatergic neurotransmission in a temporally and spatially dependent manner. To test this hypothesis, a glutamate selective mic...
Autores principales: | Hascup, Kevin N., Findley, Caleigh A., Sime, Lindsey N., Hascup, Erin R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7467928/ https://www.ncbi.nlm.nih.gov/pubmed/32879385 http://dx.doi.org/10.1038/s41598-020-71587-6 |
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