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Accurate quantification of copy-number aberrations and whole-genome duplications in multi-sample tumor sequencing data
Copy-number aberrations (CNAs) and whole-genome duplications (WGDs) are frequent somatic mutations in cancer but their quantification from DNA sequencing of bulk tumor samples is challenging. Standard methods for CNA inference analyze tumor samples individually; however, DNA sequencing of multiple s...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468132/ https://www.ncbi.nlm.nih.gov/pubmed/32879317 http://dx.doi.org/10.1038/s41467-020-17967-y |