Cargando…

FGF/FGFR signaling in health and disease

Growing evidences suggest that the fibroblast growth factor/FGF receptor (FGF/FGFR) signaling has crucial roles in a multitude of processes during embryonic development and adult homeostasis by regulating cellular lineage commitment, differentiation, proliferation, and apoptosis of various types of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xie, Yangli, Su, Nan, Yang, Jing, Tan, Qiaoyan, Huang, Shuo, Jin, Min, Ni, Zhenhong, Zhang, Bin, Zhang, Dali, Luo, Fengtao, Chen, Hangang, Sun, Xianding, Feng, Jian Q., Qi, Huabing, Chen, Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468161/ https://www.ncbi.nlm.nih.gov/pubmed/32879300 http://dx.doi.org/10.1038/s41392-020-00222-7

Ejemplares similares

Fgfr3 mutation disrupts chondrogenesis and bone ossification in zebrafish model mimicking CATSHL syndrome partially via enhanced Wnt/β-catenin signaling
por: Sun, Xianding, et al.
Publicado: (2020)

Targeting local lymphatics to ameliorate heterotopic ossification via FGFR3-BMPR1a pathway
por: Zhang, Dali, et al.
Publicado: (2021)

Expansion of FGFR3-positive nucleus pulposus cells plays important roles in postnatal nucleus pulposus growth and regeneration
por: Xu, Meng, et al.
Publicado: (2022)

FGFR3 deficient mice have accelerated fracture repair
por: Xie, Yangli, et al.
Publicado: (2017)

Long term usage of dexamethasone accelerating the initiation of osteoarthritis via enhancing the extracellular matrix calcification and apoptosis of chondrocytes
por: Chen, Liang, et al.
Publicado: (2021)

Conditional Deletion of Fgfr3 in Chondrocytes leads to Osteoarthritis-like Defects in Temporomandibular Joint of Adult Mice
por: Zhou, Siru, et al.
Publicado: (2016)

A novel FGFR1-binding peptide exhibits anti-tumor effect on lung cancer by inhibiting proliferation and angiogenesis
por: Tan, Qiaoyan, et al.
Publicado: (2018)

Adeno-Associated Virus-Mediated RNAi against Mutant Alleles Attenuates Abnormal Calvarial Phenotypes in an Apert Syndrome Mouse Model
por: Luo, Fengtao, et al.
Publicado: (2018)

Imbalanced development of anterior and posterior thorax is a causative factor triggering scoliosis
por: Chen, Bo, et al.
Publicado: (2019)

Inhibition of aberrant Hif1α activation delays intervertebral disc degeneration in adult mice
por: Wang, Zuqiang, et al.
Publicado: (2022)

FGFR3 Deficiency Causes Multiple Chondroma-like Lesions by Upregulating Hedgehog Signaling
por: Zhou, Siru, et al.
Publicado: (2015)

PTH 1-34 Ameliorates the Osteopenia and Delayed Healing of Stabilized Tibia Fracture in Mice with Achondroplasia Resulting from Gain-Of-Function Mutation of FGFR3
por: Chen, Hangang, et al.
Publicado: (2017)

Pulsed Electromagnetic Field Inhibits Synovitis via Enhancing the Efferocytosis of Macrophages
por: Ouyang, Junjie, et al.
Publicado: (2020)

The exosome-like vesicles from osteoarthritic chondrocyte enhanced mature IL-1β production of macrophages and aggravated synovitis in osteoarthritis
por: Ni, Zhenhong, et al.
Publicado: (2019)

Anemonin attenuates osteoarthritis progression through inhibiting the activation of IL‐1β/NF‐κB pathway
por: Wang, Zuqiang, et al.
Publicado: (2017)

Dstyk mutation leads to congenital scoliosis-like vertebral malformations in zebrafish via dysregulated mTORC1/TFEB pathway
por: Sun, Xianding, et al.
Publicado: (2020)

Differential Specificity of Endocrine FGF19 and FGF21 to FGFR1 and FGFR4 in Complex with KLB
por: Yang, Chaofeng, et al.
Publicado: (2012)

Role of FGF/FGFR signaling in skeletal development and homeostasis: learning from mouse models
por: Su, Nan, et al.
Publicado: (2014)

IRE1α regulates the PTHrP-IHH feedback loop to orchestrate chondrocyte hypertrophy and cartilage mineralization
por: Fan, Mengtian, et al.
Publicado: (2022)

Deformed Skull Morphology Is Caused by the Combined Effects of the Maldevelopment of Calvarias, Cranial Base and Brain in FGFR2-P253R Mice Mimicking Human Apert Syndrome
por: Luo, Fengtao, et al.
Publicado: (2017)

Bone function, dysfunction and its role in diseases including critical illness
por: Su, Nan, et al.
Publicado: (2019)

Exogenous Indian hedgehog antagonist damages intervertebral discs homeostasis in adult mice
por: Chen, Ran, et al.
Publicado: (2022)

Expression of FGF8, FGF18, and FGFR4 in Gastroesophageal Adenocarcinomas
por: Jomrich, Gerd, et al.
Publicado: (2019)

A novel fibroblast growth factor receptor 1 inhibitor protects against cartilage degradation in a murine model of osteoarthritis
por: Xu, Wei, et al.
Publicado: (2016)

Targeting the Oncogenic FGF-FGFR Axis in Gastric Carcinogenesis
por: Zhang, Jinglin, et al.
Publicado: (2019)

Generation of Fgfr3 Conditional Knockout Mice
por: Su, Nan, et al.
Publicado: (2010)

Unleashing the potential of combining FGFR inhibitor and immune checkpoint blockade for FGF/FGFR signaling in tumor microenvironment
por: Ruan, Ruiwen, et al.
Publicado: (2023)

Hyaluronic acid-FGF2-derived peptide bioconjugates for suppression of FGFR2 and AR simultaneously as an acne antagonist
por: Su, Zijian, et al.
Publicado: (2023)

Landscape of FGF/FGFR Alterations in 12,372 Chinese Cancer Patients
por: Zuo, Wei, et al.
Publicado: (2020)

Deletion of Fgfr1 in Osteoblasts Enhances Mobilization of EPCs into Peripheral Blood in a Mouse Endotoxemia Model
por: Zhang, Yaozong, et al.
Publicado: (2014)

Inhibition of FGF‐FGFR and VEGF‐VEGFR signalling in cancer treatment
por: Liu, Guihong, et al.
Publicado: (2021)

FGF19–FGFR4 Signaling in Hepatocellular Carcinoma
por: Raja, Aroosha, et al.
Publicado: (2019)

Molecular elements in FGF19 and FGF21 defining KLB/FGFR activity and specificity
por: Agrawal, Archita, et al.
Publicado: (2018)

LHX2 facilitates the progression of nasopharyngeal carcinoma via activation of the FGF1/FGFR axis
por: Xie, Tao, et al.
Publicado: (2022)

A Network Map of FGF-1/FGFR Signaling System
por: Raju, Rajesh, et al.
Publicado: (2014)

FGF /FGFR Signal Induces Trachea Extension in the Drosophila Visual System
por: Chu, Wei-Chen, et al.
Publicado: (2013)

FGF/FGFR signaling pathway involved resistance in various cancer types
por: Zhou, Yangyang, et al.
Publicado: (2020)

Dual roles of endothelial FGF-2–FGFR1–PDGF-BB and perivascular FGF-2–FGFR2–PDGFRβ signaling pathways in tumor vascular remodeling
por: Hosaka, Kayoko, et al.
Publicado: (2018)

Aberrant FGFR4 signaling worsens nonalcoholic steatohepatitis in FGF21KO mice
por: Yu, Youxi, et al.
Publicado: (2021)

Osteocyte-Specific Deletion of Fgfr1 Suppresses FGF23
por: Xiao, Zhousheng, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_3p4jpumdcpit2hmmt80t4togbo