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Canine Parvovirus is diagnosed and neutralized by chicken IgY-scFv generated against the virus capsid protein

Canine parvovirus (CPV) can cause acute and highly contagious bloody enteritis in dog. To obtain antibodies against CPV, hens were immunized with virus-like particles (VLP) of CPV-VP2. The IgY single chain fragment variables (scFv) were generated by T7 phage display system and expressed in E. coli s...

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Detalles Bibliográficos
Autores principales: Ge, Shikun, Xu, Long, Li, Ben, Zhong, Fagang, Liu, Xiang, Zhang, Xiaoying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468180/
https://www.ncbi.nlm.nih.gov/pubmed/32883344
http://dx.doi.org/10.1186/s13567-020-00832-7