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Simultaneous targeting of mitochondria and monocytes enhances neuroprotection against ischemia–reperfusion injury

Ischemia–reperfusion injury impairs the efficacy of reperfusion therapy after ischemic stroke. Cyclophilin D (CypD)-mediated openings of mitochondrial permeability transition pore (mPTP) and subsequent monocyte-mediated inflammation are considered as major mechanisms of reperfusion injury. However,...

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Detalles Bibliográficos
Autores principales:	Okahara, Arihide, Koga, Jun-ichiro, Matoba, Tetsuya, Fujiwara, Masaki, Tokutome, Masaki, Ikeda, Gentaro, Nakano, Kaku, Tachibana, Masaki, Ago, Tetsuro, Kitazono, Takanari, Tsutsui, Hiroyuki, Egashira, Kensuke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468234/ https://www.ncbi.nlm.nih.gov/pubmed/32879367 http://dx.doi.org/10.1038/s41598-020-71326-x

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