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Mechanisms and pharmacokinetic/pharmacodynamic profiles underlying the low nephrotoxicity and ototoxicity of etimicin

Etimicin (ETM), a fourth-generation aminoglycosides (AGs), is now widely clinically used in China due to its high efficacy and low toxicity. However, the mechanisms underlying its low nephrotoxicity and ototoxicity remain unclear. In the present study we compared the antibacterial and toxicity profi...

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Detalles Bibliográficos
Autores principales: Yao, Lan, Zhang, Jing-wei, Chen, Bin, Cai, Ming-min, Feng, Dong, Wang, Qi-zhi, Wang, Xin-yu, Sun, Jian-guo, Zheng, Yi-wen, Wang, Guang-ji, Zhou, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468263/
https://www.ncbi.nlm.nih.gov/pubmed/31937930
http://dx.doi.org/10.1038/s41401-019-0342-5

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