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Mechanisms and pharmacokinetic/pharmacodynamic profiles underlying the low nephrotoxicity and ototoxicity of etimicin
Etimicin (ETM), a fourth-generation aminoglycosides (AGs), is now widely clinically used in China due to its high efficacy and low toxicity. However, the mechanisms underlying its low nephrotoxicity and ototoxicity remain unclear. In the present study we compared the antibacterial and toxicity profi...
Autores principales: | Yao, Lan, Zhang, Jing-wei, Chen, Bin, Cai, Ming-min, Feng, Dong, Wang, Qi-zhi, Wang, Xin-yu, Sun, Jian-guo, Zheng, Yi-wen, Wang, Guang-ji, Zhou, Fang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468263/ https://www.ncbi.nlm.nih.gov/pubmed/31937930 http://dx.doi.org/10.1038/s41401-019-0342-5 |
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