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Snapshots of ADP-ribose bound to Getah virus macro domain reveal an intriguing choreography

Alphaviruses are (re-)emerging arboviruses of public health concern. The nsP3 gene product is one of the key players during viral replication. NsP3 comprises three domains: a macro domain, a zinc-binding domain and a hypervariable region. The macro domain is essential at both early and late stages o...

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Detalles Bibliográficos
Autores principales: Ferreira-Ramos, Ana Sofia, Sulzenbacher, Gerlind, Canard, Bruno, Coutard, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468284/
https://www.ncbi.nlm.nih.gov/pubmed/32879358
http://dx.doi.org/10.1038/s41598-020-70870-w