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Snapshots of ADP-ribose bound to Getah virus macro domain reveal an intriguing choreography
Alphaviruses are (re-)emerging arboviruses of public health concern. The nsP3 gene product is one of the key players during viral replication. NsP3 comprises three domains: a macro domain, a zinc-binding domain and a hypervariable region. The macro domain is essential at both early and late stages o...
Autores principales: | Ferreira-Ramos, Ana Sofia, Sulzenbacher, Gerlind, Canard, Bruno, Coutard, Bruno |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468284/ https://www.ncbi.nlm.nih.gov/pubmed/32879358 http://dx.doi.org/10.1038/s41598-020-70870-w |
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