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α(1)-AR overactivation induces cardiac inflammation through NLRP3 inflammasome activation
Acute sympathetic stress causes excessive secretion of catecholamines and induces cardiac injuries, which are mainly mediated by β-adrenergic receptors (β-ARs). However, α(1)-adrenergic receptors (α(1)-ARs) are also expressed in the heart and are activated upon acute sympathetic stress. In the prese...
Autores principales: | Xin, Jun-zhou, Wu, Ji-min, Hu, Guo-min, Gu, Hui-jun, Feng, Ye-nan, Wang, Shuai-xing, Cong, Wen-wen, Li, Ming-zhe, Xu, Wen-li, Song, Yao, Xiao, Han, Zhang, You-yi, Wang, Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468364/ https://www.ncbi.nlm.nih.gov/pubmed/31530901 http://dx.doi.org/10.1038/s41401-019-0305-x |
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