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Urotensin II and urantide exert opposite effects on the cellular components of atherosclerotic plaque in hypercholesterolemic rabbits

Increasing levels of plasma urotensin II (UII) are positively associated with atherosclerosis. In this study we investigated the role of macrophage-secreted UII in atherosclerosis progression, and evaluated the therapeutic value of urantide, a potent competitive UII receptor antagonist, in atheroscl...

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Detalles Bibliográficos
Autores principales: Yu, Qing-qing, Cheng, Da-xin, Xu, Li-ran, Li, Yan-kui, Zheng, Xiao-ya, Liu, Yi, Li, Ya-feng, Liu, Hao-le, Bai, Liang, Wang, Rong, Fan, Jiang-lin, Liu, En-qi, Zhao, Si-hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468446/
https://www.ncbi.nlm.nih.gov/pubmed/31685976
http://dx.doi.org/10.1038/s41401-019-0315-8