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LW-213, a newly synthesized flavonoid, induces G2/M phase arrest and apoptosis in chronic myeloid leukemia

Chronic myeloid leukemia (CML) is a clonal hematopoietic stem cell neoplasm characterized by an uncontrolled proliferation of moderately and well differentiated cells of the granulocytic lineage. LW-213, a newly synthesized flavonoid compound, was found to exert antitumor effects against breast canc...

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Detalles Bibliográficos
Autores principales: Liu, Xiao, Hu, Po, Li, Hui, Yu, Xiao-xuan, Wang, Xiang-yuan, Qing, Ying-jie, Wang, Zhan-yu, Wang, Hong-zheng, Zhu, Meng-yuan, Guo, Qing-long, Hui, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468447/
https://www.ncbi.nlm.nih.gov/pubmed/31316178
http://dx.doi.org/10.1038/s41401-019-0270-4