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The Concept of an Epilepsy Brain Bank
Epilepsy comprises more than 40 clinical syndromes affecting millions of patients and families worldwide. To decode the molecular and pathological framework of epilepsy researchers, need reliable human epilepsy and control brain samples. Brain bank organizations collecting and supplying well-documen...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468480/ https://www.ncbi.nlm.nih.gov/pubmed/32973652 http://dx.doi.org/10.3389/fneur.2020.00833 |
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author | Hernandez-Ronquillo, Lizbeth Miranzadeh Mahabadi, Hajar Moien-Afshari, Farzad Wu, Adam Auer, Roland Zherebitskiy, Viktor Borowsky, Ron Mickleborough, Marla Huntsman, Richard Vrbancic, Mirna Cayabyab, Francisco S. Taghibiglou, Changiz Carter, Alexandra Tellez-Zenteno, Jose F. |
author_facet | Hernandez-Ronquillo, Lizbeth Miranzadeh Mahabadi, Hajar Moien-Afshari, Farzad Wu, Adam Auer, Roland Zherebitskiy, Viktor Borowsky, Ron Mickleborough, Marla Huntsman, Richard Vrbancic, Mirna Cayabyab, Francisco S. Taghibiglou, Changiz Carter, Alexandra Tellez-Zenteno, Jose F. |
author_sort | Hernandez-Ronquillo, Lizbeth |
collection | PubMed |
description | Epilepsy comprises more than 40 clinical syndromes affecting millions of patients and families worldwide. To decode the molecular and pathological framework of epilepsy researchers, need reliable human epilepsy and control brain samples. Brain bank organizations collecting and supplying well-documented clinically and pathophysiologically tissue specimens are important for high-quality neurophysiology and neuropharmacology studies for epilepsy and other neurological diseases. New development in molecular mechanism and new treatment methods for neurological disorders have evoked increased demands for human brain tissue. An epilepsy brain bank is a storage source for both the frozen samples as well as the formaldehyde fixed paraffin embedded (FFPE) tissue from epilepsy surgery resections. In 2014, the University of Saskatchewan have started collecting human epilepsy brain tissues for the first time in Canada. This review highlights the necessity and importance of Epilepsy Brain bank that provides unique access for research to valuable source of brain tissue and blood samples from epilepsy patients. |
format | Online Article Text |
id | pubmed-7468480 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-74684802020-09-23 The Concept of an Epilepsy Brain Bank Hernandez-Ronquillo, Lizbeth Miranzadeh Mahabadi, Hajar Moien-Afshari, Farzad Wu, Adam Auer, Roland Zherebitskiy, Viktor Borowsky, Ron Mickleborough, Marla Huntsman, Richard Vrbancic, Mirna Cayabyab, Francisco S. Taghibiglou, Changiz Carter, Alexandra Tellez-Zenteno, Jose F. Front Neurol Neurology Epilepsy comprises more than 40 clinical syndromes affecting millions of patients and families worldwide. To decode the molecular and pathological framework of epilepsy researchers, need reliable human epilepsy and control brain samples. Brain bank organizations collecting and supplying well-documented clinically and pathophysiologically tissue specimens are important for high-quality neurophysiology and neuropharmacology studies for epilepsy and other neurological diseases. New development in molecular mechanism and new treatment methods for neurological disorders have evoked increased demands for human brain tissue. An epilepsy brain bank is a storage source for both the frozen samples as well as the formaldehyde fixed paraffin embedded (FFPE) tissue from epilepsy surgery resections. In 2014, the University of Saskatchewan have started collecting human epilepsy brain tissues for the first time in Canada. This review highlights the necessity and importance of Epilepsy Brain bank that provides unique access for research to valuable source of brain tissue and blood samples from epilepsy patients. Frontiers Media S.A. 2020-08-20 /pmc/articles/PMC7468480/ /pubmed/32973652 http://dx.doi.org/10.3389/fneur.2020.00833 Text en Copyright © 2020 Hernandez-Ronquillo, Miranzadeh Mahabadi, Moien-Afshari, Wu, Auer, Zherebitskiy, Borowsky, Mickleborough, Huntsman, Vrbancic, Cayabyab, Taghibiglou, Carter and Tellez-Zenteno. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Neurology Hernandez-Ronquillo, Lizbeth Miranzadeh Mahabadi, Hajar Moien-Afshari, Farzad Wu, Adam Auer, Roland Zherebitskiy, Viktor Borowsky, Ron Mickleborough, Marla Huntsman, Richard Vrbancic, Mirna Cayabyab, Francisco S. Taghibiglou, Changiz Carter, Alexandra Tellez-Zenteno, Jose F. The Concept of an Epilepsy Brain Bank |
title | The Concept of an Epilepsy Brain Bank |
title_full | The Concept of an Epilepsy Brain Bank |
title_fullStr | The Concept of an Epilepsy Brain Bank |
title_full_unstemmed | The Concept of an Epilepsy Brain Bank |
title_short | The Concept of an Epilepsy Brain Bank |
title_sort | concept of an epilepsy brain bank |
topic | Neurology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468480/ https://www.ncbi.nlm.nih.gov/pubmed/32973652 http://dx.doi.org/10.3389/fneur.2020.00833 |
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