Oroxindin inhibits macrophage NLRP3 inflammasome activation in DSS-induced ulcerative colitis in mice via suppressing TXNIP-dependent NF-κB pathway

Oroxindin is a flavonoid isolated from the traditional Chinese medicine Huang-Qin, which has shown various pharmacological activities including anti-inflammatory, antitumor, antioxidant, etc. Thus far, the effect of oroxindin on colonic inflammation and the underlying mechanism remain unknown. In th...

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Detalles Bibliográficos
Autores principales: Liu, Qi, Zuo, Rui, Wang, Kai, Nong, Fei-fei, Fu, Ya-jun, Huang, Shao-wei, Pan, Zeng-feng, Zhang, Yi, Luo, Xia, Deng, Xiang-liang, Zhang, Xiao-xue, Zhou, Lian, Chen, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468572/
https://www.ncbi.nlm.nih.gov/pubmed/31937929
http://dx.doi.org/10.1038/s41401-019-0335-4

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