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The Role of Zinc in Selected Female Reproductive System Disorders

Zinc is an essential microelement that plays many important functions in the body. It is crucial for the regulation of cell growth, hormone release, immunological response and reproduction. This review focuses on its importance in the reproductive system of women of reproductive and postmenopausal a...

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Autores principales: Nasiadek, Marzenna, Stragierowicz, Joanna, Klimczak, Michał, Kilanowicz, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468694/
https://www.ncbi.nlm.nih.gov/pubmed/32824334
http://dx.doi.org/10.3390/nu12082464
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author Nasiadek, Marzenna
Stragierowicz, Joanna
Klimczak, Michał
Kilanowicz, Anna
author_facet Nasiadek, Marzenna
Stragierowicz, Joanna
Klimczak, Michał
Kilanowicz, Anna
author_sort Nasiadek, Marzenna
collection PubMed
description Zinc is an essential microelement that plays many important functions in the body. It is crucial for the regulation of cell growth, hormone release, immunological response and reproduction. This review focuses on its importance in the reproductive system of women of reproductive and postmenopausal ages, not including its well described role in pregnancy. Only recently, attention has been drawn to the potential role of zinc in polycystic ovary syndrome (PCOS), dysmenorrhea, or endometriosis. This review is mainly based on 36 randomized, controlled studies on reproductive, pre- and post-menopausal populations of women and on research trying to explain the potential impact of zinc and its supplementation in the etiology of selected female reproductive system disorders. In women with PCOS, zinc supplementation has a positive effect on many parameters, especially those related to insulin resistance and lipid balance. In primary dysmenorrhea, zinc supplementation before and during each menstrual cycle seems to be an important factor reducing the intensity of menstrual pain. On the other hand, little is known of the role of zinc in endometriosis and in postmenopausal women. Therefore, further studies explaining the potential impact of zinc and its supplementation on female reproductive system would be highly advisable and valuable.
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spelling pubmed-74686942020-09-04 The Role of Zinc in Selected Female Reproductive System Disorders Nasiadek, Marzenna Stragierowicz, Joanna Klimczak, Michał Kilanowicz, Anna Nutrients Review Zinc is an essential microelement that plays many important functions in the body. It is crucial for the regulation of cell growth, hormone release, immunological response and reproduction. This review focuses on its importance in the reproductive system of women of reproductive and postmenopausal ages, not including its well described role in pregnancy. Only recently, attention has been drawn to the potential role of zinc in polycystic ovary syndrome (PCOS), dysmenorrhea, or endometriosis. This review is mainly based on 36 randomized, controlled studies on reproductive, pre- and post-menopausal populations of women and on research trying to explain the potential impact of zinc and its supplementation in the etiology of selected female reproductive system disorders. In women with PCOS, zinc supplementation has a positive effect on many parameters, especially those related to insulin resistance and lipid balance. In primary dysmenorrhea, zinc supplementation before and during each menstrual cycle seems to be an important factor reducing the intensity of menstrual pain. On the other hand, little is known of the role of zinc in endometriosis and in postmenopausal women. Therefore, further studies explaining the potential impact of zinc and its supplementation on female reproductive system would be highly advisable and valuable. MDPI 2020-08-16 /pmc/articles/PMC7468694/ /pubmed/32824334 http://dx.doi.org/10.3390/nu12082464 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Nasiadek, Marzenna
Stragierowicz, Joanna
Klimczak, Michał
Kilanowicz, Anna
The Role of Zinc in Selected Female Reproductive System Disorders
title The Role of Zinc in Selected Female Reproductive System Disorders
title_full The Role of Zinc in Selected Female Reproductive System Disorders
title_fullStr The Role of Zinc in Selected Female Reproductive System Disorders
title_full_unstemmed The Role of Zinc in Selected Female Reproductive System Disorders
title_short The Role of Zinc in Selected Female Reproductive System Disorders
title_sort role of zinc in selected female reproductive system disorders
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468694/
https://www.ncbi.nlm.nih.gov/pubmed/32824334
http://dx.doi.org/10.3390/nu12082464
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