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WDHD1 facilitates G1 checkpoint abrogation in HPV E7 expressing cells by modulating GCN5

BACKGROUND: Genomic instability is a hallmark of cancer. The G1 checkpoint allows cells to repair damaged DNA that may lead to genomic instability. The high-risk human papillomavirus (HPV) E7 gene can abrogate the G1 checkpoint, yet the mechanism is still not fully understood. Our recent study showe...

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Detalles Bibliográficos
Autores principales:	Zhou, Yunying, Pei, Fengyan, Ji, Mingyu, Zhang, Fang, Sun, Yingshuo, Zhao, Qianqian, Wang, Xiao, Hong, Yatian, Tian, Juanjuan, Wang, Yunshan, Chen, Jason J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469104/ https://www.ncbi.nlm.nih.gov/pubmed/32883234 http://dx.doi.org/10.1186/s12885-020-07287-1

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