The biological function and clinical significance of SF3B1 mutations in cancer

Spliceosome mutations have become the most interesting mutations detected in human cancer in recent years. The spliceosome, a large, dynamic multimegadalton small nuclear ribonucleoprotein composed of small nuclear RNAs associated with proteins, is responsible for removing introns from precursor mRN...

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Detalles Bibliográficos
Autores principales: Zhou, Zhixia, Gong, Qi, Wang, Yin, Li, Mengkun, Wang, Lu, Ding, Hongfei, Li, Peifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469106/
https://www.ncbi.nlm.nih.gov/pubmed/32905346
http://dx.doi.org/10.1186/s40364-020-00220-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469106/
https://www.ncbi.nlm.nih.gov/pubmed/32905346
http://dx.doi.org/10.1186/s40364-020-00220-5

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