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Detection of Amyloid β Oligomers with RNA Aptamers in App(NL-G-F/NL-G-F) Mice: A Model of Arctic Alzheimer’s Disease

[Image: see text] RNA aptamers have garnered attention for diagnostic applications due to their ability to recognize diverse targets. Oligomers of 42-mer amyloid β-protein (Aβ42), whose accumulation is relevant to the pathology of Alzheimer’s disease (AD), are among the most difficult molecules for...

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Detalles Bibliográficos
Autores principales: Obata, Yayoi, Murakami, Kazuma, Kawase, Taiji, Hirose, Kenji, Izuo, Naotaka, Shimizu, Takahiko, Irie, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469371/
https://www.ncbi.nlm.nih.gov/pubmed/32905362
http://dx.doi.org/10.1021/acsomega.0c02134