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Binding of 2-(Triazolylthio)acetamides to Metallo-β-lactamase CcrA Determined with NMR
[Image: see text] Metallo-β-lactamase (MBL)-producing bacteria resistant to β-lactam antibiotics are a serious threat to human health. Despite great efforts and important progress in the discovery of MBL inhibitors (MBLIs), there is none in clinical use. Herein, inhibitor complexes of the MBL CcrA w...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469393/ https://www.ncbi.nlm.nih.gov/pubmed/32905426 http://dx.doi.org/10.1021/acsomega.0c02187 |