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ATAD5 suppresses centrosome over-duplication by regulating UAF1 and ID1
Centrosomes are the primary microtubule-organizing centers that are important for mitotic spindle assembly. Centrosome amplification is commonly observed in human cancer cells and contributes to genomic instability. However, it is not clear how centrosome duplication is dysregulated in cancer cells....
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469630/ https://www.ncbi.nlm.nih.gov/pubmed/32594826 http://dx.doi.org/10.1080/15384101.2020.1785724 |