Unbiased translation proteomics upon cell stress

The mammalian target of rapamycin and the integrated stress response are central cellular hubs regulating translation upon stress. The precise proteins and pathway specificity of translation targets of these pathways remained largely unclear. We recently described a new method for quantitative trans...

Descripción completa

Detalles Bibliográficos
Autores principales: Klann, Kevin, Münch, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Author’s Views
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469668/
https://www.ncbi.nlm.nih.gov/pubmed/32944625
http://dx.doi.org/10.1080/23723556.2020.1763150
_version_ 1783578445864763392
author Klann, Kevin
Münch, Christian
author_facet Klann, Kevin
Münch, Christian
author_sort Klann, Kevin
collection PubMed
description The mammalian target of rapamycin and the integrated stress response are central cellular hubs regulating translation upon stress. The precise proteins and pathway specificity of translation targets of these pathways remained largely unclear. We recently described a new method for quantitative translation proteomics and found that both pathways control translation of the same sets of proteins.
format Online
Article
Text
id pubmed-7469668
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Taylor & Francis
record_format MEDLINE/PubMed
spelling pubmed-74696682020-09-28 Unbiased translation proteomics upon cell stress Klann, Kevin Münch, Christian Mol Cell Oncol Author’s Views The mammalian target of rapamycin and the integrated stress response are central cellular hubs regulating translation upon stress. The precise proteins and pathway specificity of translation targets of these pathways remained largely unclear. We recently described a new method for quantitative translation proteomics and found that both pathways control translation of the same sets of proteins. Taylor & Francis 2020-05-18 /pmc/articles/PMC7469668/ /pubmed/32944625 http://dx.doi.org/10.1080/23723556.2020.1763150 Text en © 2020 The Author(s). Published with license by Taylor & Francis Group, LLC. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.
spellingShingle Author’s Views
Klann, Kevin
Münch, Christian
Unbiased translation proteomics upon cell stress
title Unbiased translation proteomics upon cell stress
title_full Unbiased translation proteomics upon cell stress
title_fullStr Unbiased translation proteomics upon cell stress
title_full_unstemmed Unbiased translation proteomics upon cell stress
title_short Unbiased translation proteomics upon cell stress
title_sort unbiased translation proteomics upon cell stress
topic Author’s Views
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469668/
https://www.ncbi.nlm.nih.gov/pubmed/32944625
http://dx.doi.org/10.1080/23723556.2020.1763150
work_keys_str_mv AT klannkevin unbiasedtranslationproteomicsuponcellstress
AT munchchristian unbiasedtranslationproteomicsuponcellstress

Ejemplares similares