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Impact of gender, albumin, and CYP2C19 polymorphisms on valproic acid in Chinese patients: a population pharmacokinetic model

OBJECTIVE: This prospective study aimed to establish the valproic acid (VPA) population pharmacokinetic model in Chinese patients and realise personalised medication on the basis of population pharmacokinetics. METHODS: The patients’ clinical information and VPA plasma concentrations were collected...

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Detalles Bibliográficos
Autores principales: Guo, Jinlin, Huo, Yayu, Li, Fang, Li, Yuanping, Guo, Zhaojun, Han, Huaqing, Zhou, Yuhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469748/
https://www.ncbi.nlm.nih.gov/pubmed/32865063
http://dx.doi.org/10.1177/0300060520952281