Fibroblast growth factor receptor 4 increases epidermal growth factor receptor (EGFR) signaling by inducing amphiregulin expression and attenuates response to EGFR inhibitors in colon cancer

Fibroblast growth factor receptor 4 (FGFR4) is known to induce cancer cell proliferation, invasion, and antiapoptosis through activation of RAS/RAF/ERK and PI3K/AKT pathways, which are also known as major molecular bases of colon cancer carcinogenesis related with epidermal growth factor receptor (E...

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Detalles Bibliográficos
Autores principales: Hong, Chang‐Soo, Sun, Eun‐Gene, Choi, Ji‐Na, Kim, Dae‐Hwan, Kim, Jo‐Heon, Ryu, Kyung‐Hyun, Shim, Hyun‐Jeong, Hwang, Jun‐Eul, Bae, Woo‐Kyun, Kim, Hyeong‐Rok, Kim, Kyung Keun, Jung, Chaeyong, Chung, Ik‐Joo, Cho, Sang‐Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469799/
https://www.ncbi.nlm.nih.gov/pubmed/32533590
http://dx.doi.org/10.1111/cas.14526

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