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Crossroads of telomere biology and anticancer drug discovery

The telomere is the specialized nucleoprotein complex at the end of the chromosome. Its highly conserved 5′‐TTAGGG‐3′ repeats and shelterin protein complexes form a protective loop structure to maintain the integrity and stability of linear chromosomes. Although human somatic cells gradually shorten...

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Detalles Bibliográficos
Autor principal:	Seimiya, Hiroyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Review Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469838/ https://www.ncbi.nlm.nih.gov/pubmed/32579791 http://dx.doi.org/10.1111/cas.14540

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