Cargando…

Global Survey of Guidelines for the Management of Epilepsy in Pregnancy: A report from the International League Against Epilepsy Task Force on Women and Pregnancy

The ILAE Task Force on Women and Pregnancy conducted a survey among ILAE Chapters of their use of guidelines or recommendations for the management of women with epilepsy during pregnancy. A web‐based questionnaire including 10 questions was sent to the 118 ILAE Chapters in December 2017 with repeate...

Descripción completa

Detalles Bibliográficos
Autores principales: Tomson, Torbjörn, Battino, Dina, Bromley, Rebecca, Kochen, Silvia, Meador, Kimford J., Pennell, Page B., Thomas, Sanjeev V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469854/
https://www.ncbi.nlm.nih.gov/pubmed/32913945
http://dx.doi.org/10.1002/epi4.12420
_version_ 1783578479607939072
author Tomson, Torbjörn
Battino, Dina
Bromley, Rebecca
Kochen, Silvia
Meador, Kimford J.
Pennell, Page B.
Thomas, Sanjeev V.
author_facet Tomson, Torbjörn
Battino, Dina
Bromley, Rebecca
Kochen, Silvia
Meador, Kimford J.
Pennell, Page B.
Thomas, Sanjeev V.
author_sort Tomson, Torbjörn
collection PubMed
description The ILAE Task Force on Women and Pregnancy conducted a survey among ILAE Chapters of their use of guidelines or recommendations for the management of women with epilepsy during pregnancy. A web‐based questionnaire including 10 questions was sent to the 118 ILAE Chapters in December 2017 with repeated reminders until the end of February 2018. In total, 77 chapters (65%) responded, although not to all questions. Out of those responding, 68% reported having guidelines or recommendations, 34% of which were from 2014 or earlier. At least 20% of the guidelines did not include information on possible risk to cognitive development, information regarding specific risks with specific antiepileptic drugs, nor recommendations regarding selection of antiepileptic drugs. Among those responding to the question, 91% reported that recommendations were made regarding folate supplementation, but the recommended dose ranged from 0.4 mg/d to 4 mg/d or more; 34% did not include recommendations regarding drug level monitoring during pregnancy, and 19% did not include guidelines on breastfeeding. Our survey demonstrates that there is a need for the development of up‐to‐date, globally applicable recommendations for the management of epilepsy during pregnancy.
format Online
Article
Text
id pubmed-7469854
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-74698542020-09-09 Global Survey of Guidelines for the Management of Epilepsy in Pregnancy: A report from the International League Against Epilepsy Task Force on Women and Pregnancy Tomson, Torbjörn Battino, Dina Bromley, Rebecca Kochen, Silvia Meador, Kimford J. Pennell, Page B. Thomas, Sanjeev V. Epilepsia Open Special Reports The ILAE Task Force on Women and Pregnancy conducted a survey among ILAE Chapters of their use of guidelines or recommendations for the management of women with epilepsy during pregnancy. A web‐based questionnaire including 10 questions was sent to the 118 ILAE Chapters in December 2017 with repeated reminders until the end of February 2018. In total, 77 chapters (65%) responded, although not to all questions. Out of those responding, 68% reported having guidelines or recommendations, 34% of which were from 2014 or earlier. At least 20% of the guidelines did not include information on possible risk to cognitive development, information regarding specific risks with specific antiepileptic drugs, nor recommendations regarding selection of antiepileptic drugs. Among those responding to the question, 91% reported that recommendations were made regarding folate supplementation, but the recommended dose ranged from 0.4 mg/d to 4 mg/d or more; 34% did not include recommendations regarding drug level monitoring during pregnancy, and 19% did not include guidelines on breastfeeding. Our survey demonstrates that there is a need for the development of up‐to‐date, globally applicable recommendations for the management of epilepsy during pregnancy. John Wiley and Sons Inc. 2020-08-05 /pmc/articles/PMC7469854/ /pubmed/32913945 http://dx.doi.org/10.1002/epi4.12420 Text en © 2020 The Authors. Epilepsia Open published by Wiley Periodicals LLC on behalf of International League Against Epilepsy. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Special Reports
Tomson, Torbjörn
Battino, Dina
Bromley, Rebecca
Kochen, Silvia
Meador, Kimford J.
Pennell, Page B.
Thomas, Sanjeev V.
Global Survey of Guidelines for the Management of Epilepsy in Pregnancy: A report from the International League Against Epilepsy Task Force on Women and Pregnancy
title Global Survey of Guidelines for the Management of Epilepsy in Pregnancy: A report from the International League Against Epilepsy Task Force on Women and Pregnancy
title_full Global Survey of Guidelines for the Management of Epilepsy in Pregnancy: A report from the International League Against Epilepsy Task Force on Women and Pregnancy
title_fullStr Global Survey of Guidelines for the Management of Epilepsy in Pregnancy: A report from the International League Against Epilepsy Task Force on Women and Pregnancy
title_full_unstemmed Global Survey of Guidelines for the Management of Epilepsy in Pregnancy: A report from the International League Against Epilepsy Task Force on Women and Pregnancy
title_short Global Survey of Guidelines for the Management of Epilepsy in Pregnancy: A report from the International League Against Epilepsy Task Force on Women and Pregnancy
title_sort global survey of guidelines for the management of epilepsy in pregnancy: a report from the international league against epilepsy task force on women and pregnancy
topic Special Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469854/
https://www.ncbi.nlm.nih.gov/pubmed/32913945
http://dx.doi.org/10.1002/epi4.12420
work_keys_str_mv AT tomsontorbjorn globalsurveyofguidelinesforthemanagementofepilepsyinpregnancyareportfromtheinternationalleagueagainstepilepsytaskforceonwomenandpregnancy
AT battinodina globalsurveyofguidelinesforthemanagementofepilepsyinpregnancyareportfromtheinternationalleagueagainstepilepsytaskforceonwomenandpregnancy
AT bromleyrebecca globalsurveyofguidelinesforthemanagementofepilepsyinpregnancyareportfromtheinternationalleagueagainstepilepsytaskforceonwomenandpregnancy
AT kochensilvia globalsurveyofguidelinesforthemanagementofepilepsyinpregnancyareportfromtheinternationalleagueagainstepilepsytaskforceonwomenandpregnancy
AT meadorkimfordj globalsurveyofguidelinesforthemanagementofepilepsyinpregnancyareportfromtheinternationalleagueagainstepilepsytaskforceonwomenandpregnancy
AT pennellpageb globalsurveyofguidelinesforthemanagementofepilepsyinpregnancyareportfromtheinternationalleagueagainstepilepsytaskforceonwomenandpregnancy
AT thomassanjeevv globalsurveyofguidelinesforthemanagementofepilepsyinpregnancyareportfromtheinternationalleagueagainstepilepsytaskforceonwomenandpregnancy