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Unfractionated heparin attenuates endothelial barrier dysfunction via the phosphatidylinositol-3 kinase/serine/threonine kinase/nuclear factor kappa-B pathway

BACKGROUND: Vascular endothelial dysfunction is considered a key pathophysiologic process for the development of acute lung injury. In this study, we aimed at investigating the effects of unfractionated heparin (UFH) on the lipopolysaccharide (LPS)-induced changes of vascular endothelial-cadherin (V...

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Detalles Bibliográficos
Autores principales: Mu, Sheng-Tian, Tang, Jie, Ma, Jian-Qi, Zhong, Yu, Liu, Han-Zhe, Ma, Xiao-Chun, Zheng, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470014/
https://www.ncbi.nlm.nih.gov/pubmed/32649510
http://dx.doi.org/10.1097/CM9.0000000000000905