Cargando…

Gallic acid mitigates diclofenac-induced liver toxicity by modulating oxidative stress and suppressing IL-1β gene expression in male rats

CONTEXT: Diclofenac (DIC) is an NSAID and consumption of this drug creates side effects such as liver injury. Gallic acid (GA), a natural component of many plants, is used as an antioxidant agent. OBJECTIVE: This study assesses the hepatoprotective effects of GA in the rat model of DIC-induced liver...

Descripción completa

Detalles Bibliográficos
Autores principales:	Esmaeilzadeh, Mohsen, Heidarian, Esfandiar, Shaghaghi, Mehrnoosh, Roshanmehr, Hoshang, Najafi, Mohammad, Moradi, Alireza, Nouri, Ali
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470116/ https://www.ncbi.nlm.nih.gov/pubmed/32633182 http://dx.doi.org/10.1080/13880209.2020.1777169

Ejemplares similares

Antioxidant, anti-inflammatory and protective potential of gallic acid against paraquat-induced liver toxicity in male rats
por: Nouri, Ali, et al.
Publicado: (2021)

Evaluation of the effects of the hydroalcoholic extract of Terminalia chebula fruits on diazinon-induced liver toxicity and oxidative stress in rats
por: Ahmadi-Naji, Raheleh, et al.
Publicado: (2017)

Hepatorenal protective activity of Artemisia against diclofenac toxicity in male rats
por: Kadhim, Shatha Hussein, et al.
Publicado: (2022)

The Effects of Thymoquinone on Viability, and Anti-apoptotic Factors (BCL-XL, BCL-2, MCL-1) in Prostate Cancer (PC3) Cells: An In Vitro and Computer-Simulated Environment Study
por: Saffari_Chaleshtori, Javad, et al.
Publicado: (2019)

Carvacrol exerts nephroprotective effect in rat model of diclofenac-induced renal injury through regulation of oxidative stress and suppression of inflammatory response
por: Nouri, Ali, et al.
Publicado: (2021)

Protective effect of gallic acid on nicotine-induced testicular toxicity in mice
por: Jalili, Cyrus, et al.
Publicado: (2021)

Mitigation of diazinon-induced cardiovascular and renal dysfunction by gallic acid
por: Ajibade, Temitayo Olabisi, et al.
Publicado: (2016)

Antihyperlipidemic Effects of Sesamum indicum L. in Rabbits Fed a High-Fat Diet
por: Asgary, Sedigheh, et al.
Publicado: (2013)

Carvacrol Exerts Anti-Inflammatory, Anti-Oxidative Stress and Hepatoprotective Effects Against Diclofenac-Induced Liver Injury in Male Rats
por: Barzan, Molood, et al.
Publicado: (2023)

Antiproliferative and Anti-invasion Effects of Carvacrol on PC3 Human Prostate Cancer Cells through Reducing pSTAT3, pAKT, and pERK1/2 Signaling Proteins
por: Heidarian, Esfandiar, et al.
Publicado: (2019)

Mitigative effect of caffeine against diclofenac-induced hepato-renal damage and chromosomal aberrations in male albino rats
por: Anwar, Mai M., et al.
Publicado: (2022)

Therapeutic potential of Origanum vulgare leaf hydroethanolic extract against renal oxidative stress and nephrotoxicity induced by paraquat in rats
por: Sharifi-Rigi, Ali, et al.
Publicado: (2019)

Eucalyptus Globulus protects against diclofenac sodium induced hepatorenal and testicular toxicity in male rats
por: Mousa, Ahmed Abdelmoniem, et al.
Publicado: (2019)

Evaluation of the antioxidative potential of diisopropyldithiocarbamates sodium salt on diclofenac-induced toxicity in male albino rats
por: Tella, Toluwani, et al.
Publicado: (2022)

Gallic Acid Reduces Plaque Burden in Male Mice
por: Centner, Ann, et al.
Publicado: (2022)

Quercetin Synergistically Enhances the Anticancer Efficacy of Docetaxel through Induction of Apoptosis and Modulation of PI3K/AKT, MAPK/ERK, and JAK/STAT3 Signaling Pathways in MDA-MB-231 Breast Cancer Cell Line
por: Safi, Amir, et al.
Publicado: (2021)

DICLOFENAC: NEW DATA ON CHRONIC TOXICITY AND BIOCONCENTRATION IN FISH
por: Memmert, Ulrich, et al.
Publicado: (2013)

Effects of Urtica dioica hydro-alcoholic extract on blood serum glucose and lipid profiles of female Wistar rats with long-term estrogen deficiency
por: Namjou, Abdolrasoul, et al.
Publicado: (2018)

Gallic acid
por: Zhao, Jianping, et al.
Publicado: (2011)

Suppressive Impact of Anethum Graveolens Consumption on Biochemical Risk Factors of Atherosclerosis in Hypercholesterolemic Rabbits
por: Setorki, Mahbubeh, et al.
Publicado: (2013)

Activation of p53 Gene Expression and Synergistic Antiproliferative Effects of 5-Fluorouracil and β-escin on MCF7 Cells
por: Mazrouei, Raziyeh, et al.
Publicado: (2019)

Toxicity Assessment and Treatment Options of Diclofenac and Triclosan Dissolved in Water
por: Wimmerova, Lenka, et al.
Publicado: (2022)

Effects of Nigella sativa Extracts on the Lipid Profile and Uncoupling Protein-1 Gene Expression in Brown Adipose Tissue of Mice
por: Mahmoudi, Amin, et al.
Publicado: (2018)

Evaluation of the Radiosensitizing Potency of Bromelain for Radiation Therapy of 4T1 Breast Cancer Cells
por: Raeisi, Farzaneh, et al.
Publicado: (2019)

Biological Effects of Hesperetin on Interleukin-6/Phosphorylated Signal Transducer and Activator of Transcription 3 Pathway Signaling in Prostate Cancer PC3 Cells
por: Shirzad, Moein, et al.
Publicado: (2017)

Developmental Toxicity of Diclofenac and Elucidation of Gene Regulation in zebrafish (Danio rerio)
por: Chen, Jia-Bin, et al.
Publicado: (2014)

Cyclodextrin Enhances Corneal Tolerability and Reduces Ocular Toxicity Caused by Diclofenac
por: Abdelkader, Hamdy, et al.
Publicado: (2018)

Effect of cytochrome P450 inhibition on toxicity of diclofenac in chickens: Unravelling toxicity in Gyps vultures
por: Locke, Sara, et al.
Publicado: (2022)

Restorative effects of gallic acid against sub-chronic hepatic toxicity of co-exposure to zinc oxide nanoparticles and arsenic trioxide in male rats
por: Abo-EL-Sooud, Khaled, et al.
Publicado: (2023)

Differential Consequences of Unilateral Nasal Air-Puff Stimulation on Breathing Pattern and Respiratory System Mechanics in Tracheotomized Rats
por: Bakhshesh, Morteza, et al.
Publicado: (2013)

Oral pharmacokinetics of the acidic drugs, diclofenac and sulfamonomethoxine in male Shiba goats
por: ELBADAWY, Mohamed, et al.
Publicado: (2014)

DFT Study on Corrosion Inhibition by Tetrazole Derivatives: Investigation of the Substitution Effect
por: Esmaeilzadeh Khabazi, Marzieh, et al.
Publicado: (2023)

Determination of efficacy and toxicity of diclofenac microemulsion formulation for musculoskeletal pain: an observational study
por: Banh, Hoan Linh, et al.
Publicado: (2020)

Development of Novel Diclofenac Analogs Designed to Avoid Metabolic Activation and Hepatocyte Toxicity
por: Tateishi, Yasuhiro, et al.
Publicado: (2020)

The effect of Ramadan fasting on serum leptin, neuropeptide Y and insulin in pregnant women
por: Khoshdel, Abolfazl, et al.
Publicado: (2014)

Bromelain Inhibitory Effect on Colony Formation: An In vitro Study on Human AGS, PC3, and MCF7 Cancer Cells
por: Raeisi, Farzane, et al.
Publicado: (2019)

Synergetic Impact of Combined 5-Fluorouracil and Rutin on Apoptosis in PC3 Cancer Cells through the Modulation of P53 Gene Expression
por: Satari, Atefeh, et al.
Publicado: (2019)

Gallic acid pyridine monosolvate
por: Dong, Fu-Yue, et al.
Publicado: (2011)

Antioxidant protection of gallic acid against toxicity induced by Pb in blood, liver and kidney of rats
por: Reckziegel, Patrícia, et al.
Publicado: (2016)

Photostability and toxicity of finasteride, diclofenac and naproxen under simulating sunlight exposure: evaluation of the toxicity trend and of the packaging photoprotection
por: Sammartino, Maria Pia, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_b8i34l8uqv1qr6031ilrnbmero