Design, synthesis, and evaluation of 1, 4-benzodioxan-substituted chalcones as selective and reversible inhibitors of human monoamine oxidase B

The inhibition of monoamine oxidase B (MAO-B) could be an effective approach for the treatment of various neurological disorders. In this study, a series of 1, 4-benzodioxan-substituted chalcone derivatives were designed, synthesised and evaluated for their inhibitory activity against human MAO-B (h...

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Detalles Bibliográficos
Autores principales: Kong, Zhuo, Sun, Demeng, Jiang, Yanmei, Hu, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470127/
https://www.ncbi.nlm.nih.gov/pubmed/32705910
http://dx.doi.org/10.1080/14756366.2020.1797711

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470127/
https://www.ncbi.nlm.nih.gov/pubmed/32705910
http://dx.doi.org/10.1080/14756366.2020.1797711

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