Cargando…
PD-1 checkpoint blockade in advanced melanoma patients: NK cells, monocytic subsets and host PD-L1 expression as predictive biomarker candidates
Blockade of the PD-1 receptor has revolutionized the treatment of metastatic melanoma, with significant increases in overall survival (OS) and a dramatic improvement in patient quality of life. Despite the success of this approach, the number of benefitting patients is limited and there is a need fo...
Autores principales: | Pico de Coaña, Yago, Wolodarski, Maria, van der Haar Àvila, Irene, Nakajima, Takahiro, Rentouli, Stamatina, Lundqvist, Andreas, Masucci, Giuseppe, Hansson, Johan, Kiessling, Rolf |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470181/ https://www.ncbi.nlm.nih.gov/pubmed/32939320 http://dx.doi.org/10.1080/2162402X.2020.1786888 |
Ejemplares similares
-
Predicting anti-PD-1 responders in malignant melanoma from the frequency of S100A9+ monocytes in the blood
por: Rad Pour, Soudabeh, et al.
Publicado: (2021) -
High expression of ID1 in monocytes is strongly associated with phenotypic and functional MDSC markers in advanced melanoma
por: Melief, Jeroen, et al.
Publicado: (2020) -
Ipilimumab treatment decreases monocytic MDSCs and increases CD8 effector memory T cells in long-term survivors with advanced melanoma
por: de Coaña, Yago Pico, et al.
Publicado: (2017) -
Ipilimumab treatment decreases circulating Tregs and GrMDSC while enhancing CD4+ T cell activation
por: Pico de Coaña, Yago, et al.
Publicado: (2015) -
Ipilimumab treatment enhances CD4+ T cell activation while decreasing Treg and MDSC frequency in advanced melanoma patients
por: Pico de Coaña, Yago, et al.
Publicado: (2014)