Cargando…

Comparative genome analysis of novel coronavirus (SARS-CoV-2) from different geographical locations and the effect of mutations on major target proteins: An in silico insight

A novel severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) causing COVID-19 pandemic in humans, recently emerged and has exported in more than 200 countries as a result of rapid spread. In this study, we have made an attempt to investigate the SARS-CoV-2 genome reported from 13 dif...

Descripción completa

Detalles Bibliográficos
Autores principales:	Khan, Mohd Imran, Khan, Zainul A., Baig, Mohammad Hassan, Ahmad, Irfan, Farouk, Abd-ElAziem, Song, Young Goo, Dong, Jae-Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470274/ https://www.ncbi.nlm.nih.gov/pubmed/32881907 http://dx.doi.org/10.1371/journal.pone.0238344

Ejemplares similares

Screening of inhibitors against SARS-CoV-2 spike protein and their capability to block the viral entry mechanism: A viroinformatics study
por: Farouk, Abd-ElAziem, et al.
Publicado: (2021)

New quinoline-based triazole hybrid analogs as effective inhibitors of α-amylase and α-glucosidase: Preparation, in vitro evaluation, and molecular docking along with in silico studies
por: Khan, Yousaf, et al.
Publicado: (2022)

Design, Synthesis, In Silico Testing, and In Vitro Evaluation of Thiazolidinone-Based Benzothiazole Derivatives as Inhibitors of α-Amylase and α-Glucosidase
por: Khan, Shoaib, et al.
Publicado: (2022)

Effectiveness of Quaternary Ammonium in Reducing Microbial Load on Eggs
por: Chan, Hao Yuan, et al.
Publicado: (2021)

Synthesis, In Vitro Biological Evaluation and In Silico Molecular Docking Studies of Indole Based Thiadiazole Derivatives as Dual Inhibitor of Acetylcholinesterase and Butyrylchloinesterase
por: Khan, Shoaib, et al.
Publicado: (2022)

Investigating the Mechanism of Inhibition of Cyclin-Dependent Kinase 6 Inhibitory Potential by Selonsertib: Newer Insights Into Drug Repurposing
por: Baig, Mohammad Hassan, et al.
Publicado: (2022)

Molecular iodine-promoted oxidative cyclization for the synthesis of 1,3,4-thiadiazole-fused- [1,2,4]-thiadiazole incorporating 1,4-benzodioxine moiety as potent inhibitors of α-amylase and α-glucosidase: In vitro and in silico study
por: Hussain, Rafaqat, et al.
Publicado: (2022)

Multi-Spectroscopic Characterization of Human Serum Albumin Binding with Cyclobenzaprine Hydrochloride: Insights from Biophysical and In Silico Approaches
por: Baig, Mohammad Hassan, et al.
Publicado: (2019)

Synthesis, In Vitro Anti-Microbial Analysis and Molecular Docking Study of Aliphatic Hydrazide-Based Benzene Sulphonamide Derivatives as Potent Inhibitors of α-Glucosidase and Urease
por: Khan, Shoaib, et al.
Publicado: (2022)

Improving the Thermal Behavior and Flame-Retardant Properties of Poly(o-anisidine)/MMT Nanocomposites Incorporated with Poly(o-anisidine) and Clay Nanofiller
por: Ahmad, Mirza Nadeem, et al.
Publicado: (2022)

Boosted spatial charge carrier separation of binary ZnFe(2)O(4)/S-g-C(3)N(4) heterojunction for visible-light-driven photocatalytic activity and antimicrobial performance
por: Iqbal, Shahid, et al.
Publicado: (2022)

New Biologically Hybrid Pharmacophore Thiazolidinone-Based Indole Derivatives: Synthesis, In Vitro Alpha-Amylase and Alpha-Glucosidase along with Molecular Docking Investigations
por: Khan, Shoaib, et al.
Publicado: (2022)

Fabrication of a Ternary Nanocomposite g-C(3)N(4)/Cu@CdS with Superior Charge Separation for Removal of Organic Pollutants and Bacterial Disinfection from Wastewater under Sunlight Illumination
por: Afzal, Malik Imran, et al.
Publicado: (2022)

Prediction of a highly deleterious mutation E17K in AKT-1 gene: An in silico approach
por: Khan, Imran, et al.
Publicado: (2017)

Interfering PLD1-PED/PEA15 interaction using self-inhibitory peptides: An in silico study to discover novel therapeutic candidates against type 2 diabetes
por: Baig, Mohammad Hassan, et al.
Publicado: (2019)

Geographic location of CERN.
por: Jean-Luc Caron
Publicado: (1998)

Magnetic, Electronic, and Optical Studies of Gd-Doped WO(3): A First Principle Study
por: Bahadur, Ali, et al.
Publicado: (2022)

Lifestyle and geographic insights into the distinct gut microbiota in elderly women from two different geographic locations
por: Shin, Ji-Hee, et al.
Publicado: (2016)

In Silico Structural and Functional Analyses of NLRP3 Inflammasomes to Provide Insights for Treating Neurodegenerative Diseases
por: Ghazi, Behram Khan, et al.
Publicado: (2023)

Discovery of novel acetylcholinesterase inhibitors through integration of machine learning with genetic algorithm based in silico screening approaches
por: Khan, Mohd Imran, et al.
Publicado: (2023)

Full-genome sequencing and mutation analysis of SARS-CoV-2 isolated from Makassar, South Sulawesi, Indonesia
por: Massi, Muhammad Nasrum, et al.
Publicado: (2022)

Comparative Evaluation of Various Extraction Techniques for Secondary Metabolites from Bombax ceiba L. Flowering Plants along with In Vitro Anti-Diabetic Performance
por: Yasien, Sara, et al.
Publicado: (2022)

Improvement in Optoelectronic Properties of Bismuth Sulphide Thin Films by Chromium Incorporation at the Orthorhombic Crystal Lattice for Photovoltaic Applications
por: Fazal, Tanzeela, et al.
Publicado: (2022)

Simultaneous Quantification of Opioids in Blood and Urine by Gas Chromatography-Mass Spectrometer with Modified Dispersive Solid-Phase Extraction Technique
por: Yasien, Sara, et al.
Publicado: (2022)

Cation Incorporation and Synergistic Effects on the Characteristics of Sulfur-Doped Manganese Ferrites S@Mn(Fe(2)O(4)) Nanoparticles for Boosted Sunlight-Driven Photocatalysis
por: Nadeem, Sohail, et al.
Publicado: (2022)

Location, Location, Location: The Geographic Impact of Medical School on the Plastic Surgery Match
por: Glener, Adam D., et al.
Publicado: (2021)

Impact of the Double Mutants on Spike Protein of SARS-CoV-2 B.1.617 Lineage on the Human ACE2 Receptor Binding: A Structural Insight
por: Khan, Mohd Imran, et al.
Publicado: (2021)

Polycythemia, increased erythropoietin levels in a patient with renal lymphoma
por: Bhat, Riyaz Ahmad, et al.
Publicado: (2014)

A route pruning algorithm for an automated geographic location graph construction
por: Schweimer, Christoph, et al.
Publicado: (2021)

Integration of Mn-ZnFe(2)O(4) with S-g-C(3)N(4) for Boosting Spatial Charge Generation and Separation as an Efficient Photocatalyst
por: Javed, Mohsin, et al.
Publicado: (2022)

A highly explicit electrochemical biosensor for catechol detection in real samples based on copper-polypyrrole
por: Saleem, Qasar, et al.
Publicado: (2023)

Design, Synthesis, Evaluation and Thermodynamics of 1-Substituted Pyridylimidazo[1,5-a]Pyridine Derivatives as Cysteine Protease Inhibitors
por: Khan, Mohd Sajid, et al.
Publicado: (2013)

Geographical location of Point PMI2.
por: Jean-Luc Caron
Publicado: (1998)

Antioxidant and α-Amylase Inhibitory Property of Phyllanthus virgatus L.: An In Vitro and Molecular Interaction Study
por: Hashim, Arshya, et al.
Publicado: (2013)

Potential biomarkers in Japanese encephalitis from different hosts and geographical locations
por: Ziaullah M, Sain, et al.
Publicado: (2023)

Outbreak of diarrheal diseases causes mortality in different geographical locations of Bangladesh during the 2021 COVID-19 era
por: Khan, Ashraful Islam, et al.
Publicado: (2023)

Location, Location, Location: Geographic Clustering of Lower-Extremity Amputation Among Medicare Beneficiaries With Diabetes
por: Margolis, David J., et al.
Publicado: (2011)

Geographic location and phylogeny are the main determinants of the size of the geographical range in aquatic beetles
por: Abellán, Pedro, et al.
Publicado: (2011)

Genotyping of turkey coronavirus field isolates from various geographic locations in the Unites States based on the spike gene
por: Chen, Yi-Ning, et al.
Publicado: (2015)

Impact of Citral and Phloretin, Alone and in Combination, on Major Virulence Traits of Streptococcus pyogenes
por: Adil, Mohd, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_teejfcpf2p6j8jqto05iehmjg6