Treatment with galectin-1 improves myogenic potential and membrane repair in dysferlin-deficient models

Limb-girdle muscular dystrophy type 2B (LGMD2B) is caused by mutations in the dysferlin gene, resulting in non-functional dysferlin, a key protein found in muscle membrane. Treatment options available for patients are chiefly palliative in nature and focus on maintaining ambulation. Our hypothesis i...

Descripción completa

Detalles Bibliográficos
Autores principales: Vallecillo-Zúniga, Mary L., Rathgeber, Matthew F., Poulson, P. Daniel, Hayes, Spencer, Luddington, Jacob S., Gill, Hailie N., Teynor, Matthew, Kartchner, Braden C., Valdoz, Jonard, Stowell, Caleb, Markham, Ashley R., Arthur, Connie, Stowell, Sean, Van Ry, Pam M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470338/
https://www.ncbi.nlm.nih.gov/pubmed/32881965
http://dx.doi.org/10.1371/journal.pone.0238441

Ejemplares similares

Ejemplares similares