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Intraperitoneal injection of sodium pentobarbital has the potential to elicit pain in adult rats (Rattus norvegicus)

An effective and pain-free killing method is required to achieve the goal of euthanasia, a “good death”. Overdose of sodium pentobarbital (PB) by intraperitoneal (IP) injection is a widely accepted technique in laboratory rats, but questions remain regarding pain associated with administration. As P...

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Detalles Bibliográficos
Autores principales: Reimer, J. N., Schuster, C. J., Knight, C. G., Pang, D. S. J., Leung, V. S. Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470368/
https://www.ncbi.nlm.nih.gov/pubmed/32881944
http://dx.doi.org/10.1371/journal.pone.0238123