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Atom Probe Mass Spectrometry of Uranium Isotopic Reference Materials
[Image: see text] Atom probe tomography (APT)-based isotopic analyses are becoming increasingly attractive for analysis applications requiring small volumes of material and sub-micrometer length scales, such as isotope geochemistry, nuclear safety, and materials science. However, there is an open qu...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470433/ https://www.ncbi.nlm.nih.gov/pubmed/32693575 http://dx.doi.org/10.1021/acs.analchem.0c02273 |
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author | Meisenkothen, Frederick McLean, Mark Kalish, Irina Samarov, Daniel V. Steel, Eric B. |
author_facet | Meisenkothen, Frederick McLean, Mark Kalish, Irina Samarov, Daniel V. Steel, Eric B. |
author_sort | Meisenkothen, Frederick |
collection | PubMed |
description | [Image: see text] Atom probe tomography (APT)-based isotopic analyses are becoming increasingly attractive for analysis applications requiring small volumes of material and sub-micrometer length scales, such as isotope geochemistry, nuclear safety, and materials science. However, there is an open question within the atom probe community as to the reliability of atom probe isotopic and elemental analyses. Using our proposed analysis guidelines, in conjunction with an empirical calibration curve and a machine learning-based adaptive peak fitting algorithm, we demonstrate accurate and repeatable uranium isotopic analyses, via atom probe mass spectrometry, on U(3)O(8) isotopic reference materials. By using isotopic reference materials, each measured isotopic abundance value could be directly compared to a known certified reference value to permit a quantitative statement of accuracy. The isotopic abundance measurements for (235)U and (238)U in each individual APT sample were consistently within ±1.5% relative to the known reference values. The accuracy and repeatability are approaching values consistent with measurements limited primarily by Poisson counting statistics, i.e., the number of uranium atoms recorded. |
format | Online Article Text |
id | pubmed-7470433 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | American Chemical
Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-74704332020-09-04 Atom Probe Mass Spectrometry of Uranium Isotopic Reference Materials Meisenkothen, Frederick McLean, Mark Kalish, Irina Samarov, Daniel V. Steel, Eric B. Anal Chem [Image: see text] Atom probe tomography (APT)-based isotopic analyses are becoming increasingly attractive for analysis applications requiring small volumes of material and sub-micrometer length scales, such as isotope geochemistry, nuclear safety, and materials science. However, there is an open question within the atom probe community as to the reliability of atom probe isotopic and elemental analyses. Using our proposed analysis guidelines, in conjunction with an empirical calibration curve and a machine learning-based adaptive peak fitting algorithm, we demonstrate accurate and repeatable uranium isotopic analyses, via atom probe mass spectrometry, on U(3)O(8) isotopic reference materials. By using isotopic reference materials, each measured isotopic abundance value could be directly compared to a known certified reference value to permit a quantitative statement of accuracy. The isotopic abundance measurements for (235)U and (238)U in each individual APT sample were consistently within ±1.5% relative to the known reference values. The accuracy and repeatability are approaching values consistent with measurements limited primarily by Poisson counting statistics, i.e., the number of uranium atoms recorded. American Chemical Society 2020-07-22 2020-08-18 /pmc/articles/PMC7470433/ /pubmed/32693575 http://dx.doi.org/10.1021/acs.analchem.0c02273 Text en Copyright © 2020 American Chemical Society This is an open access article published under a Creative Commons Attribution (CC-BY) License (http://pubs.acs.org/page/policy/authorchoice_ccby_termsofuse.html) , which permits unrestricted use, distribution and reproduction in any medium, provided the author and source are cited. |
spellingShingle | Meisenkothen, Frederick McLean, Mark Kalish, Irina Samarov, Daniel V. Steel, Eric B. Atom Probe Mass Spectrometry of Uranium Isotopic Reference Materials |
title | Atom Probe Mass Spectrometry of Uranium Isotopic Reference
Materials |
title_full | Atom Probe Mass Spectrometry of Uranium Isotopic Reference
Materials |
title_fullStr | Atom Probe Mass Spectrometry of Uranium Isotopic Reference
Materials |
title_full_unstemmed | Atom Probe Mass Spectrometry of Uranium Isotopic Reference
Materials |
title_short | Atom Probe Mass Spectrometry of Uranium Isotopic Reference
Materials |
title_sort | atom probe mass spectrometry of uranium isotopic reference
materials |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470433/ https://www.ncbi.nlm.nih.gov/pubmed/32693575 http://dx.doi.org/10.1021/acs.analchem.0c02273 |
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