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COVID-19 complicated by hepatic dysfunction in a 28-week pregnant woman

The COVID-19 outbreak has spread across the globe at an alarming rate. As the pandemic escalates, experience of COVID-19 in pregnant women is accumulating. We present a case of COVID-19 pneumonia in a 28-week pregnant woman with a known low lying placenta. The patient had deranged liver function tes...

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Detalles Bibliográficos
Autores principales: Anness, Abigail, Siddiqui, Farah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470510/
https://www.ncbi.nlm.nih.gov/pubmed/32878840
http://dx.doi.org/10.1136/bcr-2020-237007
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author Anness, Abigail
Siddiqui, Farah
author_facet Anness, Abigail
Siddiqui, Farah
author_sort Anness, Abigail
collection PubMed
description The COVID-19 outbreak has spread across the globe at an alarming rate. As the pandemic escalates, experience of COVID-19 in pregnant women is accumulating. We present a case of COVID-19 pneumonia in a 28-week pregnant woman with a known low lying placenta. The patient had deranged liver function tests at presentation, along with elevated bile acids. We discuss the differential diagnosis of these findings, and the possible mechanisms of hepatic injury in COVID-19. The low lying placenta in this patient meant that we had to carefully consider the application of recommendations for thromboprophylaxis in pregnant COVID-19 patients. With supportive management, this patient improved enough to be discharged, and has gone on to deliver a healthy neonate at term.
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spelling pubmed-74705102020-09-15 COVID-19 complicated by hepatic dysfunction in a 28-week pregnant woman Anness, Abigail Siddiqui, Farah BMJ Case Rep New Disease The COVID-19 outbreak has spread across the globe at an alarming rate. As the pandemic escalates, experience of COVID-19 in pregnant women is accumulating. We present a case of COVID-19 pneumonia in a 28-week pregnant woman with a known low lying placenta. The patient had deranged liver function tests at presentation, along with elevated bile acids. We discuss the differential diagnosis of these findings, and the possible mechanisms of hepatic injury in COVID-19. The low lying placenta in this patient meant that we had to carefully consider the application of recommendations for thromboprophylaxis in pregnant COVID-19 patients. With supportive management, this patient improved enough to be discharged, and has gone on to deliver a healthy neonate at term. BMJ Publishing Group 2020-09-02 /pmc/articles/PMC7470510/ /pubmed/32878840 http://dx.doi.org/10.1136/bcr-2020-237007 Text en © BMJ Publishing Group Limited 2020. No commercial re-use. See rights and permissions. Published by BMJ. This article is made freely available for use in accordance with BMJ’s website terms and conditions for the duration of the covid-19 pandemic or until otherwise determined by BMJ. You may use, download and print the article for any lawful, non-commercial purpose (including text and data mining) provided that all copyright notices and trade marks are retained.https://bmj.com/coronavirus/usage
spellingShingle New Disease
Anness, Abigail
Siddiqui, Farah
COVID-19 complicated by hepatic dysfunction in a 28-week pregnant woman
title COVID-19 complicated by hepatic dysfunction in a 28-week pregnant woman
title_full COVID-19 complicated by hepatic dysfunction in a 28-week pregnant woman
title_fullStr COVID-19 complicated by hepatic dysfunction in a 28-week pregnant woman
title_full_unstemmed COVID-19 complicated by hepatic dysfunction in a 28-week pregnant woman
title_short COVID-19 complicated by hepatic dysfunction in a 28-week pregnant woman
title_sort covid-19 complicated by hepatic dysfunction in a 28-week pregnant woman
topic New Disease
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470510/
https://www.ncbi.nlm.nih.gov/pubmed/32878840
http://dx.doi.org/10.1136/bcr-2020-237007
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