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#stayhome to contain Covid-19: Neuro-SIR – Neurodynamical epidemic modeling of infection patterns in social networks

An innovative neurodynamical model of epidemics in social networks – the Neuro-SIR – is introduced. Susceptible–Infected–Removed (SIR) epidemic processes are mechanistically modeled as analogous to the activity propagation in neuronal populations. The workings of infection transmission from individu...

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Autor principal: Lymperopoulos, Ilias N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470771/
https://www.ncbi.nlm.nih.gov/pubmed/32908331
http://dx.doi.org/10.1016/j.eswa.2020.113970
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author Lymperopoulos, Ilias N.
author_facet Lymperopoulos, Ilias N.
author_sort Lymperopoulos, Ilias N.
collection PubMed
description An innovative neurodynamical model of epidemics in social networks – the Neuro-SIR – is introduced. Susceptible–Infected–Removed (SIR) epidemic processes are mechanistically modeled as analogous to the activity propagation in neuronal populations. The workings of infection transmission from individual to individual through a network of social contacts, is driven by the dynamics of the threshold mechanism of leaky integrate-and-fire neurons. Through this approach a dynamically evolving landscape of the susceptibility of a population to a disease is formed. In this context, epidemics with varying velocities and scales are triggered by a small fraction of infected individuals according to the configuration of various endogenous and exogenous factors representing the individuals’ vulnerability, the infectiousness of a pathogen, the density of a contact network, and environmental conditions. Adjustments in the length of immunity (if any) after recovery, enable the modeling of the Susceptible–Infected–Recovered–Susceptible (SIRS) process of recurrent epidemics. Neuro-SIR by supporting an impressive level of heterogeneities in the description of a population, contagiousness of a disease, and external factors, allows a more insightful investigation of epidemic spreading in comparison with existing approaches. Through simulation experiments with Neuro-SIR, we demonstrate the effectiveness of the #stayhome strategy for containing Covid-19, and successfully validate the simulation results against the classical epidemiological theory. Neuro-SIR is applicable in designing and assessing prevention and control strategies for spreading diseases, as well as in predicting the evolution pattern of epidemics.
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spelling pubmed-74707712020-09-04 #stayhome to contain Covid-19: Neuro-SIR – Neurodynamical epidemic modeling of infection patterns in social networks Lymperopoulos, Ilias N. Expert Syst Appl Article An innovative neurodynamical model of epidemics in social networks – the Neuro-SIR – is introduced. Susceptible–Infected–Removed (SIR) epidemic processes are mechanistically modeled as analogous to the activity propagation in neuronal populations. The workings of infection transmission from individual to individual through a network of social contacts, is driven by the dynamics of the threshold mechanism of leaky integrate-and-fire neurons. Through this approach a dynamically evolving landscape of the susceptibility of a population to a disease is formed. In this context, epidemics with varying velocities and scales are triggered by a small fraction of infected individuals according to the configuration of various endogenous and exogenous factors representing the individuals’ vulnerability, the infectiousness of a pathogen, the density of a contact network, and environmental conditions. Adjustments in the length of immunity (if any) after recovery, enable the modeling of the Susceptible–Infected–Recovered–Susceptible (SIRS) process of recurrent epidemics. Neuro-SIR by supporting an impressive level of heterogeneities in the description of a population, contagiousness of a disease, and external factors, allows a more insightful investigation of epidemic spreading in comparison with existing approaches. Through simulation experiments with Neuro-SIR, we demonstrate the effectiveness of the #stayhome strategy for containing Covid-19, and successfully validate the simulation results against the classical epidemiological theory. Neuro-SIR is applicable in designing and assessing prevention and control strategies for spreading diseases, as well as in predicting the evolution pattern of epidemics. Elsevier Ltd. 2021-03-01 2020-09-03 /pmc/articles/PMC7470771/ /pubmed/32908331 http://dx.doi.org/10.1016/j.eswa.2020.113970 Text en © 2020 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Lymperopoulos, Ilias N.
#stayhome to contain Covid-19: Neuro-SIR – Neurodynamical epidemic modeling of infection patterns in social networks
title #stayhome to contain Covid-19: Neuro-SIR – Neurodynamical epidemic modeling of infection patterns in social networks
title_full #stayhome to contain Covid-19: Neuro-SIR – Neurodynamical epidemic modeling of infection patterns in social networks
title_fullStr #stayhome to contain Covid-19: Neuro-SIR – Neurodynamical epidemic modeling of infection patterns in social networks
title_full_unstemmed #stayhome to contain Covid-19: Neuro-SIR – Neurodynamical epidemic modeling of infection patterns in social networks
title_short #stayhome to contain Covid-19: Neuro-SIR – Neurodynamical epidemic modeling of infection patterns in social networks
title_sort #stayhome to contain covid-19: neuro-sir – neurodynamical epidemic modeling of infection patterns in social networks
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470771/
https://www.ncbi.nlm.nih.gov/pubmed/32908331
http://dx.doi.org/10.1016/j.eswa.2020.113970
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