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Angiogenin and tRNA fragments in Parkinson’s disease and neurodegeneration

In this review, we summarise the evidence for a role of the ribonuclease angiogenin in the pathophysiology of neurodegenerative disorders, with a specific focus on Parkinson’s disease (PD). Angiogenin is a stress-induced, secreted ribonuclease with both nuclear and cytosolic activities. Loss-of-func...

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Detalles Bibliográficos
Autores principales: Prehn, Jochen H M, Jirström, Elisabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470775/
https://www.ncbi.nlm.nih.gov/pubmed/32144338
http://dx.doi.org/10.1038/s41401-020-0375-9