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Mitochondrial fatty acid synthesis coordinates oxidative metabolism in mammalian mitochondria

Cells harbor two systems for fatty acid synthesis, one in the cytoplasm (catalyzed by fatty acid synthase, FASN) and one in the mitochondria (mtFAS). In contrast to FASN, mtFAS is poorly characterized, especially in higher eukaryotes, with the major product(s), metabolic roles, and cellular function...

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Detalles Bibliográficos
Autores principales:	Nowinski, Sara M, Solmonson, Ashley, Rusin, Scott F, Maschek, J Alan, Bensard, Claire L, Fogarty, Sarah, Jeong, Mi-Young, Lettlova, Sandra, Berg, Jordan A, Morgan, Jeffrey T, Ouyang, Yeyun, Naylor, Bradley C, Paulo, Joao A, Funai, Katsuhiko, Cox, James E, Gygi, Steven P, Winge, Dennis R, DeBerardinis, Ralph J, Rutter, Jared
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2020
Materias:	Biochemistry and Chemical Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470841/ https://www.ncbi.nlm.nih.gov/pubmed/32804083 http://dx.doi.org/10.7554/eLife.58041

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