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Icariside II inhibits lipopolysaccharide-induced inflammation and amyloid production in rat astrocytes by regulating IKK/IκB/NF-κB/BACE1 signaling pathway
β-amyloid (Aβ) is one of the inducing factors of astrocytes activation and neuroinflammation, and it is also a crucial factor for the development of Alzheimer’s disease (AD). Icariside II (ICS II) is an active component isolated from a traditional Chinese herb Epimedium, which has shown to attnuate...
Autores principales: | Zheng, Yong, Deng, Yan, Gao, Jian-mei, Lv, Chun, Lang, Ling-hu, Shi, Jing-shan, Yu, Chang-yin, Gong, Qi-hai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470889/ https://www.ncbi.nlm.nih.gov/pubmed/31554962 http://dx.doi.org/10.1038/s41401-019-0300-2 |
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