IgD-Fc-Ig fusion protein, a new biological agent, inhibits T cell function in CIA rats by inhibiting IgD-IgDR-Lck-NF-κB signaling pathways

IgD-Fc-Ig fusion protein, a new biological agent, is constructed by linking a segment of human IgD-Fc with a segment of human IgG1-Fc, which specifically blocks the IgD-IgDR pathway and selectively inhibits the abnormal proliferation, activation, and differentiation of T cells. In this study we inve...

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Detalles Bibliográficos
Autores principales: Han, Le, Zhang, Xian-zheng, Wang, Chen, Tang, Xiao-yu, Zhu, Yue, Cai, Xiao-yu, Wu, Yu-jing, Shu, Jin-ling, Wang, Qing-tong, Chen, Jing-yu, Chang, Yan, Wu, Hua-xun, Zhang, Ling-ling, Wei, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470893/
https://www.ncbi.nlm.nih.gov/pubmed/31937932
http://dx.doi.org/10.1038/s41401-019-0337-2

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