Cargando…

Intact RNA structurome reveals mRNA structure-mediated regulation of miRNA cleavage in vivo

MicroRNA (miRNA)-mediated cleavage is involved in numerous essential cellular pathways. miRNAs recognize target RNAs via sequence complementarity. In addition to complementarity, in vitro and in silico studies have suggested that RNA structure may influence the accessibility of mRNAs to miRNA-induce...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Minglei, Woolfenden, Hugh C, Zhang, Yueying, Fang, Xiaofeng, Liu, Qi, Vigh, Maria L, Cheema, Jitender, Yang, Xiaofei, Norris, Matthew, Yu, Sha, Carbonell, Alberto, Brodersen, Peter, Wang, Jiawei, Ding, Yiliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470952/
https://www.ncbi.nlm.nih.gov/pubmed/32652041
http://dx.doi.org/10.1093/nar/gkaa577