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Poly(A) binding KPAF4/5 complex stabilizes kinetoplast mRNAs in Trypanosoma brucei
In Trypanosoma brucei, mitochondrial pre-mRNAs undergo 3′-5′ exonucleolytic processing, 3′ adenylation and uridylation, 5′ pyrophosphate removal, and, often, U-insertion/deletion editing. The 3′ modifications are modulated by pentatricopeptide repeat (PPR) Kinetoplast Polyadenylation Factors (KPAFs)...
Autores principales: | Aphasizheva, Inna, Yu, Tian, Suematsu, Takuma, Liu, Qiushi, Mesitov, Mikhail V, Yu, Clinton, Huang, Lan, Zhang, Liye, Aphasizhev, Ruslan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470953/ https://www.ncbi.nlm.nih.gov/pubmed/32614436 http://dx.doi.org/10.1093/nar/gkaa575 |
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