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Resolving Toxic DNA repair intermediates in every E. coli replication cycle: critical roles for RecG, Uup and RadD
DNA lesions or other barriers frequently compromise replisome progress. The SF2 helicase RecG is a key enzyme in the processing of postreplication gaps or regressed forks in Escherichia coli. A deletion of the recG gene renders cells highly sensitive to a range of DNA damaging agents. Here, we demon...
Autores principales: | Romero, Zachary J, Chen, Stefanie H, Armstrong, Thomas, Wood, Elizabeth A, van Oijen, Antoine, Robinson, Andrew, Cox, Michael M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470958/ https://www.ncbi.nlm.nih.gov/pubmed/32644157 http://dx.doi.org/10.1093/nar/gkaa579 |
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