scIGANs: single-cell RNA-seq imputation using generative adversarial networks

Single-cell RNA-sequencing (scRNA-seq) enables the characterization of transcriptomic profiles at the single-cell resolution with increasingly high throughput. However, it suffers from many sources of technical noises, including insufficient mRNA molecules that lead to excess false zero values, term...

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Detalles Bibliográficos
Autores principales: Xu, Yungang, Zhang, Zhigang, You, Lei, Liu, Jiajia, Fan, Zhiwei, Zhou, Xiaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470961/
https://www.ncbi.nlm.nih.gov/pubmed/32588900
http://dx.doi.org/10.1093/nar/gkaa506

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