Bypass of DNA interstrand crosslinks by a Rev1–DNA polymerase ζ complex

DNA polymerase ζ (Pol ζ) and Rev1 are essential for the repair of DNA interstrand crosslink (ICL) damage. We have used yeast DNA polymerases η, ζ and Rev1 to study translesion synthesis (TLS) past a nitrogen mustard-based interstrand crosslink (ICL) with an 8-atom linker between the crosslinked base...

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Detalles Bibliográficos
Autores principales: Bezalel-Buch, Rachel, Cheun, Young K, Roy, Upasana, Schärer, Orlando D, Burgers, Peter M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470978/
https://www.ncbi.nlm.nih.gov/pubmed/32633759
http://dx.doi.org/10.1093/nar/gkaa580

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470978/
https://www.ncbi.nlm.nih.gov/pubmed/32633759
http://dx.doi.org/10.1093/nar/gkaa580

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