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Bypass of DNA interstrand crosslinks by a Rev1–DNA polymerase ζ complex
DNA polymerase ζ (Pol ζ) and Rev1 are essential for the repair of DNA interstrand crosslink (ICL) damage. We have used yeast DNA polymerases η, ζ and Rev1 to study translesion synthesis (TLS) past a nitrogen mustard-based interstrand crosslink (ICL) with an 8-atom linker between the crosslinked base...
Autores principales: | Bezalel-Buch, Rachel, Cheun, Young K, Roy, Upasana, Schärer, Orlando D, Burgers, Peter M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470978/ https://www.ncbi.nlm.nih.gov/pubmed/32633759 http://dx.doi.org/10.1093/nar/gkaa580 |
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