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CDK4/6 inhibitor palbociclib overcomes acquired resistance to third‐generation EGFR inhibitor osimertinib in non‐small cell lung cancer (NSCLC)

BACKGROUND: The third‐generation EGFR‐TKI, represented by osimertinib, has been widely used in clinical practice; however, resistance eventually emerges. At present, it remains unclear whether an abnormal cell cycle is involved in acquired resistance, and whether the combination of palbociclib (CDK4...

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Detalles Bibliográficos
Autores principales:	Qin, Qiong, Li, Xiaoqing, Liang, Xingmei, Zeng, Lili, Wang, Jing, Sun, Linlin, Zhong, Diansheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons Australia, Ltd 2020
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471056/ https://www.ncbi.nlm.nih.gov/pubmed/32677256 http://dx.doi.org/10.1111/1759-7714.13521

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