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Exosomal CircPRRX1 Enhances Doxorubicin Resistance in Gastric Cancer by Regulating MiR-3064-5p/PTPN14 Signaling

PURPOSE: Gastric cancer (GC) is a malignant tumor with a high mortality rate. Drug resistance is a major obstacle to GC therapy. This study aimed to investigate the role and mechanism of exosomal circPRRX1 in doxorubicin resistance in GC. MATERIALS AND METHODS: HGC-27 and AGS cells were exposed to d...

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Detalles Bibliográficos
Autores principales: Wang, Shumin, Ping, Mei, Song, Bin, Guo, Yarong, Li, Yuanfei, Jia, Junmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471080/
https://www.ncbi.nlm.nih.gov/pubmed/32882759
http://dx.doi.org/10.3349/ymj.2020.61.9.750