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MMR Deficiency is Homogeneous in Pancreatic Carcinoma and Associated with High Density of Cd8-Positive Lymphocytes

BACKGROUND: Microsatellite instability (MSI) has emerged as a predictive biomarker for immune checkpoint inhibitor therapy. Cancer heterogeneity represents a potential obstacle for the analysis of predicitive biomarkers. MSI has been reported in pancreatic cancer, but data on the possible extent of...

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Detalles Bibliográficos
Autores principales:	Fraune, Christoph, Burandt, Eike, Simon, Ronald, Hube-Magg, Claudia, Makrypidi-Fraune, Georgia, Kluth, Martina, Büscheck, Franziska, Höflmayer, Doris, Blessin, Niclas Ch., Mandelkow, Tim, Li, Wenchao, Perez, Daniel, Izbicki, Jakob R., Wilczak, Waldemar, Sauter, Guido, Schrader, Jörg, Neipp, Michael, Mofid, Hamid, Daniels, Thies, Isbert, Christoph, Clauditz, Till S., Steurer, Stefan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2020
Materias:	Translational Research and Biomarkers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471097/ https://www.ncbi.nlm.nih.gov/pubmed/32108923 http://dx.doi.org/10.1245/s10434-020-08209-y

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