Cargando…

HDAC Inhibition Induces PD-L1 Expression in a Novel Anaplastic Thyroid Cancer Cell Line

While papillary thyroid cancer (PTC) has largely favorable prognosis, anaplastic thyroid cancer (ATC) is a rare but extremely aggressive malignancy with grim clinical outcome. Even though new therapeutic options are emerging for ATC, additional preclinical models and novel combinations are needed fo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hegedűs, Luca, Rittler, Dominika, Garay, Tamás, Stockhammer, Paul, Kovács, Ildikó, Döme, Balázs, Theurer, Sarah, Hager, Thomas, Herold, Thomas, Kalbourtzis, Stavros, Bankfalvi, Agnes, Schmid, Kurt W., Führer, Dagmar, Aigner, Clemens, Hegedűs, Balázs
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Netherlands 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471186/ https://www.ncbi.nlm.nih.gov/pubmed/32591993 http://dx.doi.org/10.1007/s12253-020-00834-y

Ejemplares similares

HDAC Inhibition Induces Cell Cycle Arrest and Mesenchymal-Epithelial Transition in a Novel Pleural-Effusion Derived Uterine Carcinosarcoma Cell Line
por: Stockhammer, Paul, et al.
Publicado: (2021)

Allosteric and ATP-Competitive MEK-Inhibition in a Novel Spitzoid Melanoma Model with a RAF- and Phosphorylation-Independent Mutation
por: Hegedüs, Luca, et al.
Publicado: (2021)

Pan-RAF and MEK vertical inhibition enhances therapeutic response in non-V600 BRAF mutant cells
por: Molnár, Eszter, et al.
Publicado: (2018)

Horizontal Combination of MEK and PI3K/mTOR Inhibition in BRAF Mutant Tumor Cells with or without Concomitant PI3K Pathway Mutations
por: Rittler, Dominika, et al.
Publicado: (2020)

The Antitumor Effect of Lipophilic Bisphosphonate BPH1222 in Melanoma Models: The Role of the PI3K/Akt Pathway and the Small G Protein Rheb
por: Rittler, Dominika, et al.
Publicado: (2019)

The FAK inhibitor BI 853520 inhibits spheroid formation and orthotopic tumor growth in malignant pleural mesothelioma
por: Laszlo, Viktoria, et al.
Publicado: (2018)

Long-Term Vemurafenib Exposure Induced Alterations of Cell Phenotypes in Melanoma: Increased Cell Migration and Its Association with EGFR Expression
por: Molnár, Eszter, et al.
Publicado: (2019)

Multicellular contractility contributes to the emergence of mesothelioma nodules
por: Tarnoki-Zach, Julia, et al.
Publicado: (2020)

Screening of Pleural Mesothelioma Cell Lines for Kinase Activity May Identify New Mechanisms of Therapy Resistance in Patients Receiving Platin-Based Chemotherapy
por: Borchert, Sabrina, et al.
Publicado: (2019)

Impact of metallothionein-knockdown on cisplatin resistance in malignant pleural mesothelioma
por: Borchert, Sabrina, et al.
Publicado: (2020)

A comparison of sample preparation strategies for biological tissues and subsequent trace element analysis using LA-ICP-MS
por: Bonta, Maximilian, et al.
Publicado: (2016)

Tumour cell PD-L1 expression is prognostic in patients with malignant pleural effusion: the impact of C-reactive protein and immune-checkpoint inhibition
por: Ghanim, Bahil, et al.
Publicado: (2020)

Implementation of an experimental isolated lung perfusion model on surgically resected human lobes
por: Slama, Alexis, et al.
Publicado: (2019)

From Bench to Bedside: Attempt to Evaluate Repositioning of Drugs in the Treatment of Metastatic Small Cell Lung Cancer (SCLC)
por: Lohinai, Zoltan, et al.
Publicado: (2016)

Circulating complement component 4d (C4d) correlates with tumor volume, chemotherapeutic response and survival in patients with malignant pleural mesothelioma
por: Klikovits, Thomas, et al.
Publicado: (2017)

Jump into a New Fold—A Homology Based Model for the ABCG2/BCRP Multidrug Transporter
por: László, Laura, et al.
Publicado: (2016)

Nintedanib and Dasatinib Treatments Induce Protective Autophagy as a Potential Resistance Mechanism in MPM Cells
por: Hegedüs, Luca, et al.
Publicado: (2022)

Prenylation Inhibition-Induced Cell Death in Melanoma: Reduced Sensitivity in BRAF Mutant/PTEN Wild-Type Melanoma Cells
por: Garay, Tamás, et al.
Publicado: (2015)

KRAS-mutation incidence and prognostic value are metastatic site-specific in lung adenocarcinoma: poor prognosis in patients with KRAS mutation and bone metastasis
por: Lohinai, Zoltan, et al.
Publicado: (2017)

The Prognostic Relevance of PMCA4 Expression in Melanoma: Gender Specificity and Implications for Immune Checkpoint Inhibition
por: Hegedüs, Luca, et al.
Publicado: (2022)

The effects of bisphosphonate and radiation therapy in bone-metastatic lung adenocarcinoma: the impact of KRAS mutation
por: Radeczky, Peter, et al.
Publicado: (2021)

Histone Deacetylase Inhibitor Treatment Increases the Expression of the Plasma Membrane Ca(2+) Pump PMCA4b and Inhibits the Migration of Melanoma Cells Independent of ERK
por: Hegedüs, Luca, et al.
Publicado: (2017)

Limited Tumor Tissue Drug Penetration Contributes to Primary Resistance against Angiogenesis Inhibitors
por: Torok, Szilvia, et al.
Publicado: (2017)

A Novel Mathematical Model Describing Adaptive Cellular Drug Metabolism and Toxicity in the Chemoimmune System
por: Tóth, Attila, et al.
Publicado: (2015)

Open Source Tools for Temporally Controlled Rodent Behavior Suitable for Electrophysiology and Optogenetic Manipulations
por: Solari, Nicola, et al.
Publicado: (2018)

Apelin promotes lymphangiogenesis and lymph node metastasis
por: Berta, Judit, et al.
Publicado: (2014)

Cell type-dependent HIF1 α-mediated effects of hypoxia on proliferation, migration and metastatic potential of human tumor cells
por: Tátrai, Enikő, et al.
Publicado: (2017)

Current therapy of KRAS-mutant lung cancer
por: Ghimessy, Aron, et al.
Publicado: (2020)

Effectiveness of Parameters in Quantifying Root Canal Morphology Change after Instrumentation with the Aid of a Microcomputed Tomography
por: Juhasz, Alexander, et al.
Publicado: (2019)

Targeting an Oncolytic Influenza A Virus to Tumor Tissue by Elastase
por: Kuznetsova, Irina, et al.
Publicado: (2017)

K-Ras prenylation as a potential anticancer target
por: Baranyi, Marcell, et al.
Publicado: (2020)

Differential recruitment of ventral pallidal e-types by behaviorally salient stimuli during Pavlovian conditioning
por: Hegedüs, Panna, et al.
Publicado: (2021)

Cellular Processing of the ABCG2 Transporter—Potential Effects on Gout and Drug Metabolism
por: Mózner, Orsolya, et al.
Publicado: (2019)

The transport pathway in the ABCG2 protein and its regulation revealed by molecular dynamics simulations
por: Nagy, Tamás, et al.
Publicado: (2020)

Stromal Expression of Heat-Shock Protein 27 Is Associated with Worse Clinical Outcome in Patients with Colorectal Cancer Lung Metastases
por: Schweiger, Thomas, et al.
Publicado: (2015)

Dataset of a study investigating autologous blood patch pleurodesis in postoperative prolonged air leaks after lung resection
por: Ploenes, Till, et al.
Publicado: (2020)

Insights into immunometabolism: A dataset correlating the (18)FDG PET/CT maximum standard uptake value of the primary tumor with the CCL18 serum level in non-small cell lung cancer
por: Dönmez, Tugba, et al.
Publicado: (2021)

KRAS Mutations Predict Response and Outcome in Advanced Lung Adenocarcinoma Patients Receiving First-Line Bevacizumab and Platinum-Based Chemotherapy
por: Ghimessy, Áron Kristof, et al.
Publicado: (2019)

Malignant pleural mesothelioma nodules remodel their surroundings to vascularize and grow
por: Kovacs, Ildiko, et al.
Publicado: (2022)

BARD1 serum autoantibodies for the detection of lung cancer
por: Pilyugin, Maxim, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_caq2av34bodkru4a77trh4392b